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姓 名: 侯一平
Name: Yi-Ping Hou
職 務(wù):教授、博士生導(dǎo)師
Duty: Professor
E-mail:houyiping@lzu.edu.cn
一、科研方向
睡眠-覺醒的機(jī)制和睡眠疾病
嗅覺中樞環(huán)路及功能
神經(jīng)毒素-肉毒素毒素作用機(jī)理及臨床應(yīng)用
二、學(xué)術(shù)團(tuán)體任職
中國解剖學(xué)會常務(wù)理事;中國神經(jīng)科學(xué)學(xué)會理事;中國睡眠研究會生理與藥理專業(yè)委員會副主任委員;甘肅省解剖學(xué)會理事長;甘肅省睡眠研究會副理事長兼秘書長;中國解剖學(xué)會學(xué)術(shù)交流與網(wǎng)絡(luò)信息工作委員會委員;中國神經(jīng)科學(xué)學(xué)會教育與繼續(xù)教育工作委員會委員;中國解剖學(xué)會人體解剖學(xué)與數(shù)字解剖分會常務(wù)委員;中國解剖學(xué)會神經(jīng)解剖學(xué)分會委員;甘肅省醫(yī)學(xué)會神經(jīng)病學(xué)學(xué)會常務(wù)理事。
三、學(xué)術(shù)期刊任職
編委:(1) The Scientific World Journal; (2) World Journal of Anesthesiology; (3) Edorium Journal of Anatomy and Embryology;(4)解剖學(xué)雜志;(5)神經(jīng)解剖學(xué)雜志;(6)解剖學(xué)研究;(7)蘭州大學(xué)學(xué)報-醫(yī)學(xué)版。
審稿人:(1) Frontiers in Neuroanatomy; (2) PLOS ONE; (3) CNS Neuroscience & Therapeutics; (4) Toxicology; (5) Clinical and Experimental Pharmacology and Physiology; (6) Journal of Hazardous Materials; (7) Iranian Red Crescent Medical Journal; (8) Neural Regeneration Research; (9) Acta Pharmacologica Sinica.
四、榮譽(yù)稱號及獎勵:
榮譽(yù)稱號
1. 甘肅省高等院?缡兰o(jì)學(xué)科帶頭人(1995);
2. 甘肅省高等院校青年教師成才獎(1996);
3. 甘肅省新長征突擊手(1997);
4. 甘肅省百優(yōu)青年(1997);
5. 甘肅'333科技人才工程'第一、第二層次首批人選(1998);
6. 甘肅省精品課程“系統(tǒng)解剖學(xué)”(2005);
7. 甘肅省精品課程“局部解剖學(xué)”(2006);
8. 甘肅省第三屆高等學(xué)校教學(xué)名師獎(2007);
9. 寶鋼優(yōu)秀教師獎(2007);
10. 甘肅省師德標(biāo)兵(2008);
11. 國務(wù)院政府特殊津貼(2008)
獎勵
1. 嗅及邊緣系統(tǒng)與腦干間的聯(lián)系(省醫(yī)學(xué)科技獎三等獎,1990);
2. 嗅結(jié)節(jié)與腦干某些核團(tuán)間的投射(省醫(yī)學(xué)科技獎三等獎1997);
3. MPTP對腦MAO-B 的作用(省醫(yī)學(xué)科技獎三等獎1999);
4. 經(jīng)皮髓核切吸術(shù)(APLD)國人應(yīng)用解剖及臨床應(yīng)用(省高?萍吉劧泉劊2004);
5. 剝奪異相睡眠導(dǎo)致大鼠學(xué)習(xí)記憶能力下降機(jī)理的研究(省醫(yī)學(xué)科技獎二等獎,2005;
6. 基于虛擬儀器技術(shù)的腦電信息綜合分析系統(tǒng)的研究(甘肅省科技進(jìn)步三等獎,2010)
五、個人簡歷
1978-1983 蘭州醫(yī)學(xué)院臨床醫(yī)學(xué)系,獲學(xué)士學(xué)位;
1983-1989 蘭州醫(yī)學(xué)院人體解剖教研室,助教;
1985-1988 蘭州醫(yī)學(xué)院解剖教研室研究生,碩士研究生,獲碩士學(xué)位;
1989-1991 蘭州醫(yī)學(xué)院解剖教研室,講師;
1992-1993 法國里昂第一大學(xué)科學(xué)院,留學(xué),導(dǎo)師:Dr. L. ASTIC;
1993-1995 法國里昂第一大學(xué)醫(yī)學(xué)院,博士后,導(dǎo)師: Prof. M. Jouvet and Dr. JS. Lin;
1995-1998 蘭州醫(yī)學(xué)院副教授;
1999-2000 加拿大蒙特利爾McGill大學(xué),訪問學(xué)者。 導(dǎo)師: Prof. B E. Jones;
1999-2004 蘭州醫(yī)學(xué)院教授;
2005- 蘭州大學(xué)基礎(chǔ)醫(yī)學(xué)院神經(jīng)科學(xué)研究所、教授(所長);人體解剖與組織胚胎研究所,教授。
六、近年主持的國家科研項(xiàng)目
國家自然科學(xué)基金面上項(xiàng)目 (81471347,2015-2018);國家自然科學(xué)基金面上項(xiàng)目 (81171254,2012-2015);國家自然科學(xué)基金面上項(xiàng)目 (81071076,2011);國家科技重大專項(xiàng)(2009ZX09503-017, 2009);國家自然科學(xué)基金面上項(xiàng)目 (30670677,2007-2009)。
七、主持的教學(xué)研究項(xiàng)目:
蘭州大學(xué)第六批重點(diǎn)建設(shè)課程“系統(tǒng)解剖學(xué)”(2005);蘭州大學(xué)雙語教學(xué)課程“局部解剖學(xué)” (2006);甘肅省精品課程“系統(tǒng)解剖學(xué)” (2005);蘭州大學(xué)本科教育質(zhì)量工程專項(xiàng)經(jīng)費(fèi)支持計(jì)劃“國家精品課培育”(2007)。
八、發(fā)表SCI論文
1. Shao YF, Zhao P, Dong CY, Li J, Kong XP, Wang HL, Dai LR, Hou YP*. Neuropeptide S facilitates mice olfactory function through activation of cognate receptor-expressing neurons in the olfactory cortex. PLoS One 2013; 8(4):e62089. (IF=4.29)
2. Shao YF, Zhang Y, Zhao P, Yan WJ, Kong XP, Fan LL, Hou YP*. Botulinum toxin type A therapy in migraine: preclinical and clinical trials. Iran Red Crescent Med J 2013; e7704 (IF=0.371)
3. Jing YH, Hou YP, Song YF, Yin J. Methylprednisolone improves the survival of new neurons following transient cerebral ischemia in rats. Acta Neurobiol Exp (Wars). 2012; 72(3):240-52. (IF=2.11)
4. Qu WM, Yue XF, Sun Y, Fan K, Chen CR, Hou YP, Urade Y, Huang ZL. Honokiol promotes non-rapid eye movement sleep via the benzodiazepine site of the GABAA receptor in mice. Br J Pharmacol 2012; 167(3):587-593. (IF= 5.067)
5. Zhao P, Shao YF, Zhang M, Fan K, Kong XP, Wang R, Hou YP*. Neuropeptide S promotes wakefulness through activation of the posterior hypothalamic histaminergic and orexinergic neurons. Neuroscience 2012; 207:218-226. (IF=3.458)
6. Hou YP, Gu JY, Shao YF, Song YF, Jing YH, Wu WS, Pu S. The characteristics of placental transfer and tissue concentrations of nickel in late gestational rats and fetuses. Placenta 2011; 32:277-282. (IF=3.693)
7. Wang XW, Gu JY, Li Z, Song YF, Wu WS, Hou YP*. Gestational age and dose influence on placental transfer of 63Ni in rats. Placenta 2010; 31:305-311. (IF=3.693)
8. Li Z, Gu JY, Wang XW, Fan QH, Ge YX, Jiao ZX, Hou YP, Wu WS. Effects of cadmium on absorption, excretion, and distribution of nickel in rats. Biol Trace Elem Res 2010; 135(1-3):211-219. (IF= 1.923)
9. Zhang X, Sun YN, Xie P, Yang XG, Hou YP* Effect of microinjecting GABAA-receptor antagonist into the tuberomammillary nucleus on the sleep-wakefulness cycle after lesion of the ventrolateral preoptic area in rats. Neural Regen Res 2009; 4(1):53-57. (IF=0.216)
10. Zhu CM, Yao XR, Zhang WS, Song YF, Hou YP*. Progressive paradoxical sleep deprivation impairs partial memory and influences motor behavior following learning tasks in rats. Neural Regen Res 2008; 3(6):598-603. (IF=0.216)
11. Wen WD, Yuan F, Wang JL, Hou YP*. Botulinum toxin therapy in the ovalbumin-sensitized rat. Neuroimmunomodulation 2007; 14(2):78-83. (IF2010=2.642)
12. Hou YP, Zhang YP, Song YF, Zhu CM, Wang YC, Xie GL. Botulinum toxin type A inhibits rat pyloric myoelectrical activity and substance P release in vivo. Can J Physiol Pharmacol 2007; 85(2): 209-214. (IF=1.849)
13. Manns ID, Lee MG, Hou YP, Jones BE. Alpha 2 adrenergic receptors on GABAergic, putative sleep-promoting basal forebrain neurons. Euro J Neurosci 2003; 18:723-727. (IF=3.658)
14. Hou YP, Manns ID, Jones BE. Immunostaining of choliergic pontomesencephallic neurons for α1 versus α2 adrenergic receptors suggests different sleep-wake state activities and roles. Neuroscience 2002; 114 (3):517-521. (IF=3.458)
15. Lin JS, Gervasoni D, Hou Y, Vanni-Mercier G, Rambert F, Frydam A, Jouvet M. Effects of amphetamine and modafinil on the sleep/wake cycle during experimental hypersomnia induced by sleep deprivation in the cat. J Sleep Res 2000; 9:89-96. (IF=3.361)
16. Hou YP, Lin JS. Effects of modafinil and amphetamine on sleep-wake cycle after sleep deprivation in cats. Acta Pharmacol Sin 1999; 20(9):813-818. (IF=2.354)
17. Hou YP, Song YF. The distribution of type B monoamine oxidase immunereactivity inhibited by i-methyl-4-penyl-1,2,3,6-tetrahydropyridine in the cat. Neurosci Bult (Chin. J. Neurosci) (1999), 15(4):279-284 (IF=1.311)
18. Lin JS, Hou Y, Rambert FA, Jouvet M. A wakening profiles of modafinil in sleep-deprived cats and its induction of brain c-fos expression pattern distinct from that caused by amphetamine or methylphenidate. Sleep Research 1997; 26:23-26
19. Lin JS, Hou Y, Jouvet M. Potential brain neuronal targets for amphetamine-, methylphenidate-, and modafinil-induced wakefulness, evidenced by c-fos immunocytochemistry in the cat. Proc Natl Acad Sci USA 1996; 93:14128-14133. (IF=9.771)
20. Lin JS, Hou Y, Sakai K, Jouvet M. Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat. J Neuroscience 1996; 16(4): 1523-1537. (IF=7.271)
21. Lin JS, Hou Y, Kitahama K, Jouvet M. Selective suppression of type B monoamine oxidase immunoreactivity in the raphe nuclei following MPTP administration in the cat, NeuroReport 1995; 6:321-324. (IF=1.822)
22. Hou Y, Giannetti N. Calcitoningene-related peptide immunoreactivity in the rat peripheral olfactory system during post-natal development. Chem Senses 1994; 16:88. (IF=2.327)
九、學(xué)術(shù)團(tuán)隊(duì)(研究生)
在校:解俊樊(博士),王燦,任文婷,辛樂,崔光富。
畢業(yè): 張維勝,張福康,張小兵,張永平,袁芳,文衛(wèi)東,尤 紅,張毅,何建宏,王觸靈,趙永靈,張建東,張曉英,穆繼英,楊旭光,閻文軍,汪玉堂,李衛(wèi),李彩霞,徐桂中, 周媛媛,郭文杰,張春林,柴爾青,李萍,廉會娟,孫祎娜,張欣,王獻(xiàn)文,謝 鵬,宗曉健,谷俊英,任衛(wèi)萍,李寧,范坤,張 敏,李曉俠,趙鵬(博士),孔祥攀,邵玉峰(博士),戴麗蓉,董朝玉,王海亮,李靖。
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