華中農(nóng)業(yè)大學(xué)生命科學(xué)技術(shù)學(xué)院導(dǎo)師介紹：孫明

導(dǎo)師信息來源：中國(guó)考研網(wǎng) 2015-07-14　相關(guān)院校：華中農(nóng)業(yè)大學(xué)

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姓名

孫明

性別

男

職稱

教授

學(xué)位

博士

電話

027-87283455

郵箱

m98sun@mail.hzau.edu.cn

工作單位

生命科學(xué)技術(shù)學(xué)院，農(nóng)業(yè)微生物學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室

研究方向

微生物農(nóng)藥，芽胞桿菌分子生物學(xué)

教育經(jīng)歷

1992/09—1995/12,  華中農(nóng)業(yè)大學(xué) 土化系/生命科學(xué)技術(shù)學(xué)院，微生物專業(yè), 博士
1988/09—1991/07,  華中農(nóng)業(yè)大學(xué) 土化系，微生物專業(yè)，碩士
1984/09—1988/07,  武漢大學(xué) 生物系，微生物專業(yè), 本科(學(xué)士)

主要職歷

1991/09—現(xiàn)在,     華中農(nóng)業(yè)大學(xué)土化系/生命科學(xué)技術(shù)學(xué)院微生物專業(yè)，助教，講師, 副教授, 教授, 博士生導(dǎo)師
2004/05—2004/11,  香港大學(xué)生物多樣性和生態(tài)學(xué)系，香港裘槎基金會(huì)(The Croucher Foundation) 訪問學(xué)者
2002/07—2003/01,  美國(guó) Cornell University微生物系，國(guó)家留學(xué)基金高級(jí)訪問學(xué)者
1997/10—1998/10,  新加坡 Institute of Molecular Agrobiology, 中新合作項(xiàng)目訪問學(xué)者
1997/06—1997/09,  加拿大University of Waterloo化工系和生物系，UNESCO-ASM資助訪問學(xué)者
1994/05—1994/11,  美國(guó)The Ohio State University 生化系，WHO資助訪問學(xué)者

科研成果

1) Wang P, Zhang C, Zhu Y, Deng Y, Guo S, Peng D, Ruan L, Sun M*. (2013) The resolution and regeneration of a cointegrate plasmid reveals a model for plasmid evolution mediated by conjugation and oriT site-specific recombination. Environ Microbiol, 15(12):3305-3318.

2) Zheng J, Peng D, Song X, Ruan L, Mahillon J, Sun M*. (2013) Differentiation of Bacillus anthracis, B. cereus, and B. thuringiensis on the basis of the csaB gene reflects host source. Appl Environ Microbiol, 79(12):3860-3386.

3) Luo X, Chen L, Huang Q, Zheng J, Zhou W, Peng D, Ruan L, Sun M*. (2013) Bacillus thuringiensis metalloproteinase Bmp1 functions as a nematicidal virulence factor. Appl Environ Microbiol, 79(2):460-468.

4) Zheng J, Peng D, Ruan L, Sun M*. (2013) Evolution and dynamics of megaplasmids with genome sizes larger than 100 kb in the Bacillus cereus group. BMC Evol Biol, 13:262.

5) Wang Y, Peng D, Dong Z, Zhu L, Guo S, Sun M*. (2013) Cloning and analysis of a large plasmid pBMB165 from Bacillus thuringiensis revealed a novel plasmid organization. PLoS One, 8(12):e81746.

6) Ye W, Zhu L, Liu Y, Crickmore N, Peng D, Ruan L, Sun M*. (2012) Mining new crystal protein genes from Bacillus thuringiensis on the basis of mixed plasmid-enriched genome sequencing and a computational pipeline. Appl Environ Microbiol, 78(14):4795-4801.

7) Wang F, Liu Y, Zhang F, Chai L, Ruan L, Peng D, Sun M*. (2012) Improvement of crystal solubility and increasing toxicity against Caenorhabditis elegans by Asparagine substitution in Block 3 of Bacillus thuringiensis crystal protein Cry5Ba. Appl Environ Microbiol, 78(20):7197-7204.

8) Zhang F, Peng D, Ye X, Yu Z, Hu Z, Ruan L, Sun M*. (2012) In vitro uptake of 140 kDa Bacillus thuringiensis nematicidal crystal proteins by the second stage juvenile of Meloidogyne hapla. PLoS One, 7(6):e38534.

9) Peng D, Wang F, Li N, Zhang Z, Song R. Zhu Z, Ruan L, Sun M*. (2011) Single cysteine substitution in Bacillus thuringiensis Cry7Ba1 improves the crystal solubility and produces toxicity to Plutella xylostella larvae. Environ Microbiol, 13(10):2820-2831.

10) Luo Y, Ruan L, Zhao C, Wang C, Peng D, Sun M*. (2011) Validation of the intact Zwittermicin A biosynthetic gene cluster and discovery of a complementary resistance mechanism in Bacillus thuringiensis. Antimicrob Agents Chemother, 55(9):4161-4169.

11) Peng D, Qiu D, Ruan L, Zhou C, Sun M*. (2011) Protein elicitor PemG1 from Magnaporthe grisea induces SAR in plants through the salicylic acid and Ca²⁺-related signaling pathways. Mol Plant Microbe Interact, 24(10):1239-1246.

12) Zhu Y, Ji F, Shang H, Zhu Q, Wang P, Xu C, Deng Y,Peng D, Ruan L, Sun M*. (2011) Gene clusters located on two large plasmids determine spore crystal association (SCA) in Bacillus thuringiensis subsp. finitimus strain YBT-020. PloS One, 6(11):e27164.

13) Zhong C, Peng D, Ye W, Chai L, Qi J, Yu Z, Ruan L, Sun M*. (2011) Determination of plasmid copy number reveals the total plasmid DNA amount is greater than the chromosome DNA amount in Bacillus thuringiensis YBT-1520. PLoS One, 6(1):e16025.

14) Peng D, Chai L, Wang F, Zhang F, Ruan L, Sun M*. (2011) Synergistic activity between Bacillus thuringiensis Cry6Aa and Cry55Aa toxins against Meloidogyne incognita. Microb Biotechnol, 4(6):794-798.

15) Liu X, Ruan L, Hu Z, Peng D, Cao S, Zheng J, Liu Y, Yu Z, Sun M*. (2010) Genome wide screening revealed the genetic determinants of an antibiotic insecticide in bacillus thuringiensis. J Biol Chem, 285:39191-39200.

16) Peng D, Xu X, Ruan L, Yu Z, Sun M*. (2010) Enhancing Cry1Actoxicity by expression of the Helicoverpa armigera cadherin fragment in Bacillus thuringiensis. Res Microbiol, 161:383-389.

17) Peng D, Xu X, Ye W, Yu Z, Sun M*. (2010) Helicoverpa armigera cadherin fragment enhances Cry1Acinsecticidal activity by facilitating toxin-oligomer formation. Appl Microbiol Biotechnol,85(4):1033-1040.

18) Ban H, Chai X, Lin Y, Zhou Y, Peng D, Zhou Y, Zou Y, Yu Z, Sun M*. (2009) Transgenic Amorphophallus konjac expressing synthesized acyl-homoserine lactonase (aiiA) gene exhibit enhanced resistance to soft rot disease. Plant Cell Rep, 28(12):1847-1855.

19) Fang S, Wang L, Guo W, Zhang X, Peng D, Luo C, Yu Z, Sun M*. (2009) Bacillus thuringiensis Bel protein synergizes the toxicity of Cry1Acprotein to Helicoverpa armigera larvae by degrading insect intestinal mucin. Appl Environ Microbiol, 75(16): 5237-5243.

20) Ji F, Zhu Y, Ju S, Zhang R, Yu Z, Sun M*. (2009) Promoters of crystal protein genes do not control crystal formation inside exosporium of Bacillus thurin giensis subsp. finitimus strain YBT-020. FEMS Microbiol Lett, 300(1):11-17.

21) Liu X, Peng D, Luo Y, Ruan L, Yu Z, Sun M*. (2009) Construction of an Escherichia coli to Bacillus thuringiensis shuttle vector for large DNA fragments. Appl Microbiol Biotechnol, 82(4):765-772.

22) Peng D, Luo Y, Guo S, Zeng H, Ju S, Yu Z, Sun M*. (2009) Elaboration of an electroporation protocol for larger plasmids and wild-type strains in Bacillus thuringiensis. J Appl Microbiol, 106:1849-1858.

23) Guo G, Zhou Z, Ma Q, Liu J, Zhu L, Yu Z, Sun M*. (2008) A new group of parasporal inclusions encoded by S-layer gene of Bacillus thuringiensis. FEMS Microbiol Lett, 282(1):1-7.

24) Guo S, Liu M, Peng D, Ji S, Wang P,Yu Z, Sun M*. (2008) New strategy for isolating novel nematicidal crystal protein genes from Bacillus thuringiensis strain YBT-1518. Appl Environ Microbiol, 74(22):6997-7001.

25) Liu X, Zhu S, Ye W, Ruan L, Yu Z, Zhao C, Sun M*. (2008) Genetic characterization of two putative toxin-antitoxin systems on cryptic plasmids from Bacillus thuringiensis strain YBT-1520. J Microbiol Biotechnol, 18(10):1630-1633.

26) Liu M, Li S, Hu S, Zhao C, Bi D, Sun M*. (2008) Display of avian influenza virus nucleoprotein on Bacillus thuringiensis cell surface using CTC as a fusion partner. Appl Microbiol Biotechnol, 78(4):669-676.

27) Peng D, Zhou C, Chen S, Ruan L, Yu Z, Sun M*. (2008) Toxicological safety assessment of genetically modified Bacillus thuringiensis with additional N-Acyl homoserine lactonase gene. Environ Toxicol Chem, 27(1): 173-180.

28) Song R, Peng D, Yu Z, Sun M*. (2008) Carboxy-terminal half of Cry1Ccan help vegetative insecticidal protein to form inclusion bodies in the mother cell of Bacillus thuringiensis. Appl Microbiol Biotechnol, 80: 647-654.

29) Yu Z, Bai P, Ye W, Zhang F, Ruan L, Yu Z, Sun M*. (2008) A novel negative regulatory factor for nematicidal Cry protein gene expression in Bacillus thuringiensis. J Microbiol Biotechnol, 18(6):1033-1039.

30) Yu Z, Liu B, Zou X, Yu Z, Sun M*. (2008) Establish a bioassay to assess nematicidal effect of Bacillus thuringiensis Crystalprotein against Meloidogyne hapla. Acta Phytopathologica Sinica, 38(2):219-224.

31) Zhang L, Hu C, Ye W, Zhu D, Yu Z, Zhuo R, Sun M*. (2008) The copper-resistant bacterium ACU isolated from the rhizosphere of Eichhornia crassipes (Mart.) increased the endurance of Potamogeton crispus L. to copper toxicity. J Appl Microbiol, 105:1034-1043.

32) Zhao C, Song C, Luo Y, Yu Z, Sun M*. (2008) L-2,3-Diaminopropionate: One of the building blocks for the biosynthesis of Zwittermicin A in Bacillus thuringiensis subsp. kurstaki strain YBT-1520. FEBS Lett, 582 (20): 3125-3131.

33) Zhao C, Zeng H, Yu Z, Sun M*. (2008) N-acyl homoserine lactonase promotes prevention of Erwinia virulence with Zwittermicin A-producing strain Bacillus cereus. Biotechnol Bioeng,100(3):599-603.

34) Peng D, Chen S, Ruan L, Li L, Yu Z, Sun M. (2007) Safety assessment of transgenic Bacillus thuringiensis with VIP insecticidal protein gene by feeding studies. Food Chem Toxicol, 45:1179-1185.

35) Huang J, Han D, Yu Z, Sun M. (2007) A novel cryptic plasmid pBMB175 from Bacillus thuringiensis subsp. tenebrionis YBT-1765. Arch Microbiol, 188:47-53.

36) Zhao C, Luo Y, Song C, Liu Z, Chen S, Yu Z, Sun M. (2007) Identification of three Zwittermicin A biosynthesis-related genes from Bacillus thuringiensis subsp. kurstaki strain YBT-1520. Arch Microbiol, 187:313-319.

37) Zhang L, Ruan L, Hu C, Wu H, Chen S, Yu Z, Sun M. (2007) Fusion of the genes for AHL-lactonase and S-layer protein in Bacillus thuringiensis increases its ability to inhibit soft rot caused by Erwinia carotovora. Appl Microbiol Biotechnol,74:667-675.

38) Zhou Y, Ye WX, Zhou Y, Zhu CG, Sun M, Yu ZN. (2006) Ethanol tolerance, yield of melanin, swarming motility and growth are correlated with the expression levels of aiiA gene in Bacillus thuringiensis. Enzyme Microb Technol, 38:967-974.

39) Zhu CG, C. Ruan LF, Peng DH, Yu ZN, Sun M (2006) Vegetative insecticidal protein enhancing the toxicity of Bacillus thuringiensis subsp kurstaki against Spodoptera exigue. Lett Appl Microbiol, 42: 109-114.

40) Huang J, Guo S, Mahillon J, Van der Auwera GA, Wang L, Han D, Yu Z, Sun M. (2006) Molecular characterization of a DNA fragment harboring the replicon of pBMB165 from Bacillus thuringiensis subsp. tenebrionis. BMC Genomics, 7:270.

41) Zhu C, Yu Z, Sun M. (2006) Restraining Erwinia virulence by expression of N-acyl homoserine lactonase gene pro3A-aiiA in Bacillus thuringiensis subsp leesis. Biotechnol Bioeng, 95(3):526-532.

42) 孫明(主編) 基因工程(第二版), 高等教育出版社, 63萬字, 2013.

備注

2000年入選教育部“跨世紀(jì)優(yōu)秀人才培養(yǎng)計(jì)劃”，2011年入選農(nóng)業(yè)部農(nóng)業(yè)科研杰出人才及其創(chuàng)新團(tuán)隊(duì), 2013年入選湖北省教學(xué)名師，2002年享受國(guó)務(wù)院政府特殊津貼待遇�，F(xiàn)任農(nóng)業(yè)微生物學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室副主任, 中國(guó)微生物學(xué)會(huì)理事兼農(nóng)業(yè)微生物學(xué)專業(yè)委員會(huì)副主任、湖北省暨武漢市微生物學(xué)會(huì)常務(wù)理事兼農(nóng)業(yè)微生物學(xué)專業(yè)委員會(huì)主任，第二屆微生物學(xué)名詞審定委員會(huì)委員，農(nóng)業(yè)部肥料登記評(píng)審委員會(huì)委員，《氨基酸和生物資源》期刊主編。曾任國(guó)家自然科學(xué)基金委員會(huì)第12屆專家評(píng)審組成員。曾獲“湖北省技術(shù)發(fā)明一等獎(jiǎng)”、“湖北省自然科學(xué)獎(jiǎng)三等獎(jiǎng)”、“教育部提名國(guó)家自然科學(xué)獎(jiǎng)二等獎(jiǎng)”和“武漢市科技進(jìn)步獎(jiǎng)二等獎(jiǎng)”等獎(jiǎng)項(xiàng)。

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