Lab Director II, Bioactive Small Molecules (BASM) Lab

Center for Organic Chemistry (COC)

Email: lipengfei@mail.xjtu.edu.cn

Tel: +86-29-83395337

Employment

May/2014- Lab Director II, Bioactive Small Molecules (BASM) Lab, Center for Organic Chemistry (COC), Frontier Institute of Science and Technology (FIST), Xi’an Jiaotong University (XJTU), Xi’an, China

Nov/2011- Apr/2014    Group Leader I, Bioactive Small Molecules (BASM) Lab, Center for Organic Chemistry (COC), Frontier Institute of Science and Technology (FIST), Xi’an Jiaotong University (XJTU), Xi’an, China

Mar/2010 – Oct/2011  Postdoctoral Associate (Advisor: Prof. Stephen L. Buchwald), Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA

Apr/2005 – Sep/2006  Research chemist, Basilea Pharmaceutica (China) Ltd, Haimen, China

Jul/2004 – Mar/2005   Research chemist, Chinese Wisdom Institute of Medicine and Wisdom, Pharmaceutica Co. Ltd, Haimen, China

Education

Oct/2006 – Feb/2010 Ph.D. in Organic Chemistry (Advisor: Prof. Dirk Menche), Dissertation: Total synthesis of etnangien and studies towards the total synthesis of rhizopodin, Heidelberg University, Heidelberg, and Helmholtz Center for Infection, Research (HZI), Braunschweig, Germany

Sep/2001 – Jun/2004 M.S. in Organic Chemistry (Advisor: Prof. Zheng-Ming Li), Dissertation: Synthesis and biological activities of novel sulfonylurea compounds, Nankai University, Tianjin, China

Sep/1997 – Jul/2001  B.S. in Chemistry, Shanxi Normal University, Linfen, China

Honor

Feb/2010 The highest honor (summa cum laude) for the Ph.D. dissertation in, Heidelberg University, Germany

Research Interests

Homogeneous Catalysis • Medicinal Chemistry • Natural Products• Flow Chemistry

☆ Development of novel catalytic reactions for efficient construction of functionalized complex molecules that may be used as chemical probes in chemical biology or as organic materials

☆ Total synthesis of bioactive natural products and their analogs for drug discovery and development

☆ Continuous microflow synthesis for more user-friendly and more sustainable, efficient processes

Publications

1. Guanghu Tong, Zhi Liu, Pengfei Li,* Stereocontrolled Construction of the Tricyclic Framework of Tiglianes and Daphnanes by an Oxidative Dearomatization Approach, Org. Lett. 2014, 16, doi: 10.1021/ol5008263.