河北大學化學與環(huán)境科學學院研究生導師王克讓介紹如下：

一、個人簡介

王克讓，男，1979年，博士，教授，博導，讀博士期間師從南開大學劉育教授(2006~2009年)，讀碩士期間師從鄭州大學張雁冰教授(2003~2006年)，2009年到河北大學工作，主要從事功能超分子納米組裝體構(gòu)筑和識別研究、基于生物效應的熒光傳感研究和抗腫瘤化合物的合成及作用機制研究等。目前主持國

家自然科學基金和河北省自然科學基金等8項。2016年獲河北省杰出青年基金。2016年入選河北省“三三三人才工程”三層次人選。在Adv. Funct. Mater., Chem. Commun., ACS Macro Lett., Chem. Eur. J.和Biosens. Bioelectron.等上發(fā)表論文三十幾篇，授權(quán)發(fā)明專利6項。

聯(lián)系方式：kerangwang@163.com

二、主講課程及研究方向

1. 主講課程：有機化學

2. 研究方向：超分子化學，化學生物學

三、代表性論文

1) Chun-Miao Zhao, Ke-Rang Wang*, Chong Wang, Xu He, Xiao-Liu Li*. Cooling-induced NIR emission enhancement and targeting fluorescence imaging of bi-perylene monoimide and glycodendrimer conjugates. ACS Macro Lett., 2019, 8, 381-386.

2) Jiu-Kai Xiong, Ke-Rang Wang,* Kai-Xin Wang, Tian-Lei Han, Hong-Yu Zhu, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Fluorescent enhancement sensing of Cadmium (II) ion based on a perylene bisimide derivative. Sens. Actuators B Chem., 2019, 297, 126802.

3) Juan-Juan Li, Ke-Rang Wang*, Ren-Feng Li, Jian-Xing Yang, Min Li, Hong-Xin Zhang, Zhi-Ran Cao, Xiao-Liu Li*. Synthesis, self-assembly behaviours and multivalent glycosidase inhibition effect of deoxynojirimycin modified perylene bisimide derivatives. J. Mater. Chem. B, 2019, 7, 1270-1275.

4) Min Li, Ke-Rang Wang*, Jian-Xing Yang, Ya-Tong Peng, Yi-Xuan Liu, Hong-Xin Zhang, Xiao-Liu Li*. Supramolecular azasugar clusters based on an amphiphilic fatty-acid-deoxynojirimycin derivative as multivalent glycosidase inhibitors. J. Mater. Chem. B, 2019, 7, 1379-1383.

5) Xiao Chen, Ya-Nan Wang, Rui-Xue Rong, Chun-Miao Zhao, Xiao-Liu Li*, Ke-Rang Wang*. Synthesis, thermos-responsive behavior of cyclodextrin modified bi-perylene monoimide derivative. Dyes Pigments, 2019, 160, 779-786.

6) Qi Xu, Jia-Li Wang, Ya-Li Luo, Juan-Juan Li, Ke-Rang Wang*, Xiao-Liu Li*. Host-guest interactions and controllable capture and release of proteins based on cationic perylene bisimides. Chem. Commun., 2017, 53, 2241-2244.

7) Guo-Jing Cao, Rui-Xue Rong, Ya-Nan Wang, Qi Xu, Ke-Rang Wang*, Xiao-Liu Li*. Synthesis and Photodynamic therapy of Mono-mannose Modified Perylene Bisimide Bridged Permethyl-b-CDs. Dyes Pigments, 2017, 136, 569-576.

8) Ke-Rang Wang*, Zi-Bo Yang, Xiao-Liu Li*. High excimer-state emission of perylene bisimides and its recognition of latent fingerprints. Chem. Eur. J., 2015, 21, 5680-5684. (Frontispieces)

9) Ke-Rang Wang*, Dan Han, Guo-Jing Cao, Xiao-Liu Li*.Synthesis and predetermine supramoecular chirality of carbohydrates functionalized perylene bisimide derivatives. Chem. Asian J., 2015, 10, 1204-1214.

10)Ke-Rang Wang*, Hong-Wei An, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Synthesis of biocompatible glycodendrimer based on fluorescent perylene bisimides and its bioimaging. Macromol. Rapid. Commun., 2014, 35, 727-734.

11) Ke-Rang Wang*, Hong-Wei An, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Fluorescence turn-on sensing of protei based on mannose funtioalized perylee bsmides and its fluorescence imaging. Biosens. Bioelectron., 2014, 58, 27-32.

12) Ke-Rang Wang, Yue-Qng Wan, Hong-Wei An, Jin-Cao Zhang, Xiao-Liu Li*. A triazatruxen-based glycoclusters as a fluorescent sensor for Concanavalin A. Chm. Eur. J., 2013, 19, 2903-2909.

13) Ke-Rang Wang, Hong-Wei An, Ling, Wu, Jin-Chao Zhang, Xiao-Liu Li*. Ciral self-assembly of lactose functionalized perylene bisimides as multivalent glycocluster. Chem. Commun., 2012, 48, 5644-5646.

14) Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang, Yu Liu*. Excitonic coupling interations in the self-assemby of perylene-bridged bis(beta-cyclodextrin)s and porphyrin. Chem. Commun., 2012, 48, 3644-3646.

15) Ke-Rang Wang*, Hong-Wei An, Yue-Qing Wang, Jin-Chao Zhang, Xiao-Liu Li*. Multivalent glycoclusters constructed by chial self-assembly of mannose functionalized perylene bisimide. Org. Bimol. Chem., 2013, 11, 1007-1012.

16) Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang, Zhan-Hu Sun, Yu Liu*. Molecuar aggregtion behavior of perylene-bridged bis(beta-cyclodextrin)s and its electron interactions upon selective binding with aromatic guests. J. Phys. Chem. B, 2010, 114, 101-106.

17) Yu Liu*, Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang. Supramolecular assembly of peryene bisimide with beta-cyclodextrin grafts as solid-state fluorescent sensor for vapor detection. Adv. Funct. Mater., 2009, 19, 2230-2235.

四、科研項目

1)國家自然科學基金(面上項目)：苝-環(huán)糊精-糖類超分子多效價糖基組裝體的構(gòu)筑、識別和靶向給藥研究，項目編號：21372059，起止時間：2014-2017，主持，結(jié)題。

2) 河北省自然科學基金(杰出青年基金)：苝酰亞胺-野尻毒素超分子多效價糖苷酶抑制劑的研究，項目編號: B2016201254，起止時間：2016/01-2018/12，主持，結(jié)題.

3)國家自然科學基金(青年基金)：苝-糖類衍生物超分子多效價組裝體的構(gòu)筑及與凝集素作用研究，項目編號：21002020，起止時間：2011-2013，主持，結(jié)題。

4)河北省自然科學基金：苝-糖類衍生物超分子多效價組裝體的構(gòu)筑及與凝集素的識別研究，項目編號：B2011201052，起止時間：2011-2013， 主持，結(jié)題。

5)河北省自然科學基金：多胺連接萘酰亞胺類和二氯乙酰胺類抗腫瘤化合物的合成及性質(zhì)研究，項目編號：B2012201041，起止時間：2012-2014，主持，結(jié)題。

6)河北省高等學校科學技術(shù)研究項目(優(yōu)秀青年基金)：苝-環(huán)糊精-糖類多效價糖基組裝體的構(gòu)筑和性質(zhì)研究，項目編號：YQ2013006，起止時間：2013-2015，主持，結(jié)題。