湯朝暉
單位：中國(guó)科學(xué)院長(zhǎng)春應(yīng)用化學(xué)研究所生態(tài)環(huán)境高分子材料重點(diǎn)實(shí)驗(yàn)室
地址：吉林省長(zhǎng)春市人民大街5625號(hào)
郵編：130022
電話：0431-85262116

個(gè)人簡(jiǎn)歷  Personalresume 
湯朝暉博士研究員
工作單位：中國(guó)科學(xué)院長(zhǎng)春應(yīng)用化學(xué)研究所，生態(tài)環(huán)境高分子材料重點(diǎn)實(shí)驗(yàn)室
學(xué)習(xí)經(jīng)歷
1999–2005中國(guó)科學(xué)院長(zhǎng)春應(yīng)用化學(xué)研究所，高分子化學(xué)與物理專業(yè)，理學(xué)博士，導(dǎo)師：陳學(xué)思研究員；
1995–1999湘潭大學(xué)化學(xué)系，理學(xué)學(xué)士；
工作經(jīng)歷
2015–研究員，中國(guó)科學(xué)院長(zhǎng)春應(yīng)用化學(xué)研究所；
2009–2014副研究員，中國(guó)科學(xué)院長(zhǎng)春應(yīng)用化學(xué)研究所；
2007–2008博士后，美國(guó)紐約州立大學(xué)石溪分校（StateUniversityofNewYorkatStonyBrook），合作導(dǎo)師：朱鵬年（BenjaminChu），蕭守道（BenjaminS.Hsiao）；
2005–2006研究助理，英國(guó)帝國(guó)理工學(xué)院（ImperialCollegeLondon），合作導(dǎo)師：VCGibson。
研究興趣
生物醫(yī)用高分子材料，藥物緩控釋
學(xué)術(shù)論文與專利情況
發(fā)表SCI研究論文80余篇，包括ProgressinPolymerScience,ChemicalScience,Biomateials,JournalofControlledRelease等，他引2000余次，授權(quán)專利30項(xiàng)。
個(gè)人榮譽(yù)
1. 2015年入選中國(guó)科學(xué)院青年創(chuàng)新促進(jìn)會(huì)優(yōu)秀會(huì)員；
2. 2011年入選中國(guó)科學(xué)院青年創(chuàng)新促進(jìn)會(huì)會(huì)員；
3. 湯朝暉，可降解醫(yī)用高分子材料的基礎(chǔ)及應(yīng)用研究，吉林省科技進(jìn)步獎(jiǎng)，一等獎(jiǎng)，排名第7，2011。
4. 湯朝暉，聚乳酸新材料關(guān)鍵技術(shù)研發(fā)與產(chǎn)業(yè)化應(yīng)用，中國(guó)石油與化學(xué)工業(yè)聯(lián)合會(huì)技術(shù)發(fā)明獎(jiǎng)，一等獎(jiǎng)，排名第6，2011。

主持或參加科研項(xiàng)目（課題）
1. 國(guó)家自然科學(xué)基金面上項(xiàng)目，2016年，高分子納米化CD47抗體用于惡性腫瘤的研究，62萬元，主持；
2. 中國(guó)科學(xué)院青年創(chuàng)新促進(jìn)會(huì)優(yōu)秀會(huì)員，2015年，優(yōu)秀會(huì)員人才專項(xiàng)經(jīng)費(fèi)，150萬元，主持；
3. 國(guó)家自然科學(xué)基金面上項(xiàng)目，51373168，物理化學(xué)性質(zhì)和腫瘤種類對(duì)高分子納米粒子在小鼠體內(nèi)代謝和分布的影響研究，2014/01–2017/12，80萬元，主持；
4. 國(guó)家科技重大專項(xiàng)重大新藥創(chuàng)制，2014ZX09507-009，IPT-ZHW155的臨床前研究，2014/01–2016/12，40.5萬元，參加（子課題副組長(zhǎng)）；
5. 吉林省醫(yī)藥產(chǎn)業(yè)發(fā)展專項(xiàng)資金項(xiàng)目，20130727050YY，聚谷氨酸接枝聚乙二醇藥用輔料及順鉑膠束制劑的研究和開發(fā)，2013/06–2016/05，50萬元，主持；
6. 國(guó)家科技重大專項(xiàng)重大新藥創(chuàng)制，2013ZX09J13110-11B，基于生物可降解高分子電紡絲技術(shù)的戰(zhàn)傷救治藥物體系，2013/01–2015/12，110萬元參加（子課題副組長(zhǎng)）；
7. 吉林省科技發(fā)展計(jì)劃項(xiàng)目，科技支撐計(jì)劃，重點(diǎn)科技攻關(guān)項(xiàng)目，20130206066GX，用于抗腫瘤藥物靶向控釋的高分子載體材料的研究和開發(fā)，2013/01–2015/12，18萬元，主持；
8. 國(guó)家自然科學(xué)基金面上項(xiàng)目，51173184，氧化還原和pH雙敏感的納米藥物控釋系統(tǒng)及其克服腫瘤多藥耐藥性研究，2012/01–2015/12，65萬元，主持；
9. 中國(guó)科學(xué)院青年創(chuàng)新促進(jìn)會(huì)會(huì)員，2011年，會(huì)員人才專項(xiàng)經(jīng)費(fèi)，40萬元，主持；
10. 國(guó)家自然科學(xué)青年基金，2009年，具有生物分子識(shí)別功能可生物降解高分子材料的合成與應(yīng)用，23萬元，主持。
學(xué)術(shù)論文與書籍章節(jié)目錄
[1]Y.Zhang,C.Xiao,J.Ding,M.Li,X.Chen,Z.Tang,X.Zhuang,X.Chen,Acomparativestudyoflinear,Y-shapedandlinear-dendriticmethoxypoly(ethyleneglycol)-block-polyamidoamine-block-poly(l-glutamicacid)blockcopolymersfordoxorubicindeliveryinvitroandinvivo,ActaBiomater.40(2016)243-253.
[2]H.Yu,Z.Tang,M.Li,W.Song,D.Zhang,Y.Zhang,Y.Yang,H.Sun,M.Deng,X.Chen,Cisplatinloadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)complexnanoparticlesforpotentialcancertherapy:preparation,invitroandinvivoevaluation,JBiomedNanotechnol.12(1)(2016)69-78.
[3]Y.Wang,S.Lv,M.Deng,Z.Tang,X.Chen,Acharge-conversionalintracellular-activatedpolymericprodrugfortumortherapy,Polym.Chem.7(2016)2253-2263.
[4]Z.Tang,C.He,H.Tian,J.Ding,B.S.Hsiao,B.Chu,X.Chen,Polymericnanostructuredmaterialsforbiomedicalapplications,Prog.Polym.Sci.60(2016)86-128.
[5]W.Song,Z.Tang,D.Zhang,X.Wen,S.Lv,Z.Liu,M.Deng,X.Chen,SolidTumorTherapyUsingaCannonandPawnCombinationStrategy,Theranostics6(7)(2016)1023-1030.
[6]W.Song,Z.Tang,D.Zhang,M.Li,J.Gu,X.Chen,Acooperativepolymericplatformfortumor-targeteddrugdelivery,ChemicalScience7(1)(2016)728-736.
[7]W.Song,Z.Tang,N.Shen,H.Yu,Y.Jia,D.Zhang,J.Jiang,C.He,H.Tian,X.Chen,Combiningdisulfiramandpoly(l-glutamicacid)-cisplatinconjugatesforcombatingcisplatinresistance,J.Control.Release231(2016)94-102.
[8]W.Song,Z.Tang,T.Lei,X.Wen,G.Wang,D.Zhang,M.Deng,X.Tang,X.Chen,StableloadinganddeliveryofdisulfiramwithmPEG-PLGA/PCLmixednanoparticlesfortumortherapy,Nanomed.Nanotechnol.Biol.Med.12(2)(2016)377-86.
[9]Y.Niu,W.Song,D.Zhang,Z.Tang,M.Deng,X.Chen,Functionalcomputer-to-platenear-infraredabsorbersashighlyefficientphotoacousticdyes,ActaBiomater.43(2016)262-8.
[10]C.He,Z.Tang,H.Tian,X.Chen,Co-deliveryofchemotherapeuticsandproteinsforsynergistictherapy,Adv.DrugDel.Rev.98(2016)64-76.
[11]J.Chen,L.Lin,Z.Guo,C.Xu,Y.Li,H.Tian,Z.Tang,C.He,X.Chen,N-IsopropylacrylamideModifiedPolyethyleniminesasEffectivesiRNACarriersforCancerTherapy,JournalofNanoscienceandNanotechnology16(6)(2016)5464-5469.
[12]Z.Ahmad,S.Lv,Z.Tang,A.Shah,X.Chen,Methoxypoly(ethyleneglycol)-block-poly(glutamicacid)-graft-6-(2-nitroimidazole)hexylaminenanoparticlesforpotentialhypoxia-responsivedeliveryofdoxorubicin,J.Biomater.Sci.Polym.Ed.27(1)(2016)40-54.
[13]馬麗莉,邵俊,楊晨光,湯朝暉,陳學(xué)思,PDLA-PBS-PDLA三嵌段共聚物的合成及性能,高等學(xué)�；瘜W(xué)學(xué)報(bào)36(11)(2015)2329-2334.
[14]H.Yu,Z.Tang,D.Zhang,W.Song,Y.Zhang,Y.Yang,Z.Ahmad,X.Chen,Pharmacokinetics,biodistributionandinvivoefficacyofcisplatinloadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)complexnanoparticlesfortumortherapy,J.Control.Release205(2015)89-97.
[15]H.Yu,Z.Tang,D.Zhang,W.Song,T.Duan,J.Gu,X.Chen,Poly(ornithine‐co‐arginine‐co‐glycine‐co‐asparticAcid):PreparationviaNCAPolymerizationanditsPotentialasaPolymericTumor‐PenetratingAgent,Macromol.Biosci.15(6)(2015)829–838.
[16]H.Yu,Z.Tang,W.Song,D.Zhang,Y.Zhang,X.Chen,Co-administrationofiRGDenhancingtheanticancerefficacyofcisplatin-loadedpolypeptidenanoparticles,J.Control.Release213(2015)e145-e146.
[17]H.Y.YifeiLi,HaiSun,JianguoLiu,ZhaohuiTang,DanWang,LianyouYu,XuesiChen,Cisplatin-loadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)nanoparticlesasapotentialchemotherapeuticagentagainstosteosarcoma,Chin.J.Polym.Sci.33(5)(2015)763-771.
[18]W.Song,Z.Tang,D.Zhang,H.Yu,X.Chen,CoadministrationofVascularDisruptingAgentsandNanomedicinestoEradicateTumorsfromPeripheralandCentralRegions,Small11(31)(2015)3755-3761.
[19]W.Song,Z.Tang,D.Zhang,N.Burton,W.Driessen,X.Chen,Comprehensivestudiesofpharmacokineticsandbiodistributionofindocyaninegreenandliposomalindocyaninegreenbymultispectraloptoacoustictomography,RSCAdv.5(5)(2015)3807-3813.
[20]C.Shi,H.Yu,D.Sun,L.Ma,Z.Tang,Q.Xiao,X.Chen,Cisplatin-loadedpolymericnanoparticles:Characterizationandpotentialexploitationforthetreatmentofnon-smallcelllungcarcinoma,ActaBiomater.18(2015)68–76.
[21]M.Q.Li,Z.H.Tang,Y.Zhang,S.X.Lv,Q.S.Li,X.S.Chen,TargeteddeliveryofcisplatinbyLHRH-peptideconjugateddextrannanoparticlessuppressesbreastcancergrowthandmetastasis,ActaBiomater.18(2015)132-143.
[22]M.Li,Z.Tang,D.Zhang,H.Sun,H.Liu,Y.Zhang,Y.Zhang,X.Chen,Doxorubicin-loadedpolysaccharidenanoparticlessuppressthegrowthofmurinecolorectalcarcinomaandinhibitthemetastasisofmurinemammarycarcinomainrodentmodels,Biomaterials51(0)(2015)161-172.
[23]B.Feng,Z.Xu,F.Zhou,H.Yu,Q.Sun,D.Wang,Z.Tang,H.Yu,Q.Yin,Z.Zhang,Y.Li,Nearinfraredlight-actuatedgoldnanorodswithcisplatin-polypeptidewrappingfortargetedtherapyoftriplenegativebreastcancer,Nanoscale7(36)(2015)14854-64.
[24]R.Zhao,X.Li,B.Sun,Y.Zhang,D.Zhang,Z.Tang,X.Chen,C.Wang,Electrospunchitosan/sericincompositenanofiberswithantibacterialpropertyaspotentialwounddressings,Int.J.Biol.Macromol.68(2014)92-97.
[25]H.Yu,Z.Tang,W.Song,M.Deng,X.Chen,CurrentStatusandFutureProspectsofPolymericNanocarrierforTumorTargeting,Chem.J.Chin.Univ.-Chin.35(5)(2014)903-916.
[26]W.Song,Z.Tang,D.Zhang,Y.Zhang,H.Yu,M.Li,S.Lv,H.Sun,M.Deng,X.Chen,Anti-tumorefficacyofc(RGDfK)-decoratedpolypeptide-basedmicellesco-loadedwithdocetaxelandcisplatin,Biomaterials35(9)(2014)3005-3014.
[27]W.Song,Z.Tang,M.Li,S.Lv,H.Sun,M.Deng,H.Liu,X.Chen,Polypeptide-basedcombinationofpaclitaxelandcisplatinforenhancedchemotherapyefficacyandreducedside-effects,ActaBiomater.10(3)(2014)1392-1402.
[28]J.Shao,Z.Tang,J.Sun,G.Li,X.Chen,LinearandFour-ArmedPoly(L-lactide)-block-poly(D-lactide)CopolymersandTheirStereocomplexationwithPoly(lactide)s,JournalofPolymerSciencePartB-PolymerPhysics52(23)(2014)1560-1567.
[29]Z.Qu,R.Duan,X.Pang,B.Gao,X.Li,Z.Tang,X.Wang,X.Chen,LivingandStereoselectivePolymerizationofRac-LactidebyBimetallicAluminumSchiff-BaseComplexes,JournalofPolymerScienceParta-PolymerChemistry52(9)(2014)1344-1352.
[30]S.Lv,Z.Tang,D.Zhang,W.Song,M.Li,J.Lin,H.Liu,X.Chen,Well-definedpolymer-drugconjugateengineeredwithredoxandpH-sensitivereleasemechanismforefficientdeliveryofpaclitaxel,J.Control.Release194(2014)220-227.
[31]S.Lv,Z.Tang,M.Li,J.Lin,W.Song,H.Liu,Y.Huang,Y.Zhang,X.Chen,Co-deliveryofdoxorubicinandpaclitaxelbyPEG-polypeptidenanovehicleforthetreatmentofnon-smallcelllungcancer,Biomaterials35(23)(2014)6118-6129.
[32]S.Lv,W.Song,Z.Tang,M.Li,H.Yu,H.Hong,X.Chen,Charge-ConversionalPEG-PolypeptidePolyionicComplexNanoparticlesfromSimpleBlendingofaPairofOppositelyChargedBlockCopolymersasanIntelligentVehicleforEfficientAntitumorDrugDelivery,Mol.Pharm.11(5)(2014)1562-1574.
[33]Q.Li,S.Lv,Z.Tang,M.Liu,D.Zhang,Y.Yang,X.Chen,Aco-deliverysystembasedonpaclitaxelgraftedmPEG-b-PLGloadedwithdoxorubicin:Preparation,invitroandinvivoevaluation,Int.J.Pharm.471(1–2)(2014)412-420.
[34]M.-q.Li,Z.-h.Tang,C.Wang,Y.Zhang,H.-t.Cui,X.-s.Chen,Efficientside-chainmodificationofdextranviabase-catalyzedepoxidering-openingandthiol-eneclickchemistryinaqueousmedia,Chin.J.Polym.Sci.32(8)(2014)969-974.
[35]M.Li,Z.Tang,Y.Zhang,S.Lv,H.Yu,D.Zhang,H.Hong,X.Chen,LHRH-peptideconjugateddextrannanoparticlesfortargeteddeliveryofcisplatintobreastcancer,J.Mat.Chem.B2(22)(2014)3490-3499.
[36]M.Li,Z.Tang,S.Lv,W.Song,H.Hong,X.Jing,Y.Zhang,X.Chen,CisplatincrosslinkedpH-sensitivenanoparticlesforefficientdelivery.ofdoxorubicin,Biomaterials35(12)(2014)3851-3864.
[37]M.Li,Z.Tang,J.Lin,Y.Zhang,S.Lv,W.Song,Y.Huang,X.Chen,SynergisticAntitumorEffectsofDoxorubicin-LoadedCarboxymethylCelluloseNanoparticleinCombinationwithEndostarforEffectiveTreatmentofNon-Small-CellLungCancer,Adv.Healthc.Mater.3(11)(2014)1877-1888.
[38]Z.Guo,H.Tian,L.Lin,J.Chen,C.He,Z.Tang,X.Chen,HydrophobicPolyalanineModifiedHyperbranchedPolyethylenimineasHighEfficientpDNAandsiRNACarrier,Macromol.Biosci.14(10)(2014)1406-1414.
[39]J.Chen,J.Xia,H.Tian,Z.Tang,C.He,X.Chen,Thermo-/pH-dualresponsivepropertiesofhyperbranchedpolyethyleniminegraftedbyphenylalanine,Arch.Pharm.Res.37(1)(2014)142-148.
[40]Z.Ahmad,Z.Tang,A.Shah,S.Lv,D.Zhang,Y.Zhang,X.Chen,CisplatinLoadedMethoxyPoly(ethyleneglycol)-block-Poly(L-glutamicacid-co-L-Phenylalanine)NanoparticlesagainstHumanBreastCancerCell,Macromol.Biosci.14(9)(2014)1337-1345.
[41]L.Zhao,C.Xiao,J.Ding,P.He,Z.Tang,X.Pang,X.Zhuang,X.Chen,Facileone-potsynthesisofglucose-sensitivenanogelviathiol-eneclickchemistryforself-regulateddrugdelivery,ActaBiomater.9(5)(2013)6535-6543.
[42]L.Zhao,J.Ding,C.Xiao,P.He,Z.Tang,X.Chen,Phenylboronicacidfunctionalizedpolypeptidemicellesforglucose-responsiveinsulinreleaseatphysiologicalpH,J.Control.Release172(1)(2013)E110-E110.
[43]S.Lv,M.Li,Z.Tang,W.Song,H.Sun,H.Liu,X.Chen,Doxorubicin-loadedamphiphilicpolypeptide-basednanoparticlesasanefficientdrugdeliverysystemforcancertherapy,ActaBiomater.9(12)(2013)9330-9342.
[44]M.Li,Z.Tang,H.Sun,J.Ding,W.Song,X.Chen,pHandreductiondual-responsivenanogelcross-linkedbyquaternizationreactionforenhancedcellularinternalizationandintracellulardrugdelivery,Polym.Chem.4(4)(2013)1199-1207.
[45]M.Li,W.Song,Z.Tang,S.Lv,L.Lin,H.Sun,Q.Li,Y.Yang,H.Hong,X.Chen,NanoscaledPoly(L-glutamicacid)/Doxorubicin-AmphiphileComplexaspH-responsiveDrugDeliverySystemforEffectiveTreatmentofNonsmallCellLungCancer,AcsAppliedMaterials&Interfaces5(5)(2013)1781-1792.
[46]M.Li,S.Lv,Z.Tang,W.Song,H.Yu,H.Sun,H.Liu,X.Chen,Polypeptide/DoxorubicinHydrochloridePolymersomesPreparedThroughOrganicSolvent-freeTechniqueasaSmartDrugDeliveryPlatform,Macromol.Biosci.13(9)(2013)1150-1162.
[47]D.Li,H.Sun,J.Ding,Z.Tang,Y.Zhang,W.Xu,X.Zhuang,X.Chen,Polymerictopologyandcompositionconstrainedpolyether-polyestermicellesfordirectionalantitumordrugdelivery,ActaBiomater.9(11)(2013)8875-8884.
[48]Y.Huang,Z.Tang,X.Zhang,H.Yu,H.Sun,X.Pang,X.Chen,pH-TriggeredCharge-ReversalPolypeptideNanoparticlesforCisplatinDelivery:PreparationandInVitroEvaluation,Biomacromolecules14(6)(2013)2023-2032.
[49]P.He,C.-w.Zhao,C.-s.Xiao,Z.-h.Tang,X.-s.Chen,Thermosensitivepolyioncomplexmicellespreparedbyself-assemblyoftwooppositelychargeddiblockcopolymers,Chin.J.Polym.Sci.31(2)(2013)318-324.
[50]P.He,H.Liu,Z.Tang,M.Deng,Y.Yang,X.Pang,X.Chen,Poly(esteramide)blendmicrospheresfororalinsulindelivery,Int.J.Pharm.455(1-2)(2013)259-266.
[51]C.He,Z.Tang,H.Tian,X.Chen,ProgressintheDevelopmentofBiomedicalPolymerMaterialsFabricatedby3-DimensionalPrintingTechnology,ActaPolymericaSinica(6)(2013)722-732.
[52]J.Guo,X.Li,H.Yu,Z.Tang,X.Tang,C.Cai,J.Xu,H.Xu,Theanti-melanomaefficiencyoftheintratumoralinjectionofcucurbitacin-loadedsustained-releasecarriers:APLGAparticlesystem,J.Pharm.Sci.102(8)(2013)2550-2563.
[53]B.Gao,R.Duan,X.Pang,X.Li,Z.Qu,Z.Tang,X.Zhuang,X.Chen,StereoselectiveRing-OpeningPolymerizationofrac-LactidesCatalyzedbyAluminumHemi-SalenComplexes,Organometallics32(19)(2013)5435-5444.
[54]L.Zhao,J.Ding,C.Xiao,P.He,Z.Tang,X.Pang,X.Zhuang,X.Chen,Glucose-sensitivepolypeptidemicellesforself-regulatedinsulinreleaseatphysiologicalpH,J.Mater.Chem.22(24)(2012)12319-12328.
[55]H.Tian,Z.Tang,X.Zhuang,X.Chen,X.Jing,Biodegradablesyntheticpolymers:Preparation,functionalizationandbiomedicalapplication,Prog.Polym.Sci.37(2)(2012)237-280.
[56]W.Song,C.Xiao,L.Cui,Z.Tang,X.Zhuang,X.Chen,FacileconstructionoffunctionalbiosurfaceviaSI-ATRPand"clickglycosylation",ColloidSurf.B-Biointerfaces93(2012)188-194.
[57]W.Song,Z.Tang,M.Li,S.Lv,H.Yu,L.Ma,X.Zhuang,Y.Huang,X.Chen,TunablepH-SensitivePoly(beta-aminoester)sSynthesizedfromPrimaryAminesandDiacrylatesforIntracellularDrugDelivery,Macromol.Biosci.12(10)(2012)1375-1383.
[58]W.Song,M.Li,Z.Tang,Q.Li,Y.Yang,H.Liu,T.Duan,H.Hong,X.Chen,Methoxypoly(ethyleneglycol)-block-Poly(L-glutamicacid)-LoadedCisplatinandaCombinationWithiRGDfortheTreatmentofNon-Small-CellLungCancers,Macromol.Biosci.12(11)(2012)1514-1523.
[59]D.Li,J.X.Ding,Z.H.Tang,H.Sun,X.L.Zhuang,J.Z.Xu,X.S.Chen,InvitroevaluationofanticancernanomedicinesbasedondoxorubicinandamphiphilicY-shapedcopolymers,Int.J.Nanomedicine7(2012)2687-2697.
[60]P.He,Z.Tang,L.Lin,M.Deng,X.Pang,X.Zhuang,X.Chen,NovelBiodegradableandpH-SensitivePoly(esteramide)MicrospheresforOralInsulinDelivery,Macromol.Biosci.12(4)(2012)547-556.
[61]C.He,X.Zhuang,Z.Tang,H.Tian,X.Chen,Stimuli-SensitiveSyntheticPolypeptide-BasedMaterialsforDrugandGeneDelivery,Adv.Healthc.Mater.1(1)(2012)48-78.
[62]湯朝暉,陳學(xué)思,新型藥控/緩釋材料,中國(guó)新材料產(chǎn)業(yè)發(fā)展報(bào)告（2010）2011.
[63]X.-l.Zhuang,H.-y.Yu,Z.-h.Tang,K.Oyaizu,H.Nishide,X.-s.Chen,PolymerizationoflacticO-carboxylicanhydrideusingorganometalliccatalysts,Chin.J.Polym.Sci.29(2)(2011)197-202.
[64]L.Zhao,J.Ding,P.He,C.Xiao,Z.Tang,X.Zhuang,X.Chen,AnefficientpHsensitiveoralinsulindeliverysystemenhancedbydeoxycholicacid,J.Control.Release152(2011)E184-E186.
[65]W.Wang,J.Ding,C.Xiao,Z.Tang,D.Li,J.Chen,X.Zhuang,X.Chen,SynthesisofAmphiphilicAlternatingPolyesterswithOligo(ethyleneglycol)SideChainsandPotentialUseforSustainedReleaseDrugDelivery,Biomacromolecules12(7)(2011)2466-2474.
[66]J.Ding,X.Zhuang,C.Xiao,Y.Cheng,L.Zhao,C.He,Z.Tang,X.Chen,Preparationofphoto-cross-linkedpH-responsivepolypeptidenanogelsaspotentialcarriersforcontrolleddrugdelivery,J.Mater.Chem.21(30)(2011)11383-11391.
[67]J.Ding,C.Xiao,L.Zhao,Y.Cheng,L.Ma,Z.Tang,X.Zhuang,X.Chen,Poly(L-glutamicacid)GraftedwithOligo(2-(2-(2-methoxyethoxy)ethoxy)ethylmethacrylate):ThermalPhaseTransition,SecondaryStructure,andSelf-Assembly,JournalofPolymerScienceParta-PolymerChemistry49(12)(2011)2665-2676.
[68]J.Ding,C.Xiao,L.Yan,Z.Tang,X.Zhuang,X.Chen,X.Jing,pHanddualredoxresponsivenanogelbasedonpoly(l-glutamicacid)aspotentialintracellulardrugcarrier,J.Control.Release152(2011)E11-E13.
[69]J.Ding,C.Xiao,Z.Tang,X.Zhuang,X.Chen,HighlyEfficient"GraftingFrom"analpha-HelicalPolypeptideBackbonebyAtomTransferRadicalPolymerization,Macromol.Biosci.11(2)(2011)192-198.
[70]C.Xiao,C.Zhao,P.He,Z.Tang,X.Chen,X.Jing,FacileSynthesisofGlycopolypeptidesbyCombinationofRing-OpeningPolymerizationofanAlkyne-SubstitutedN-carboxyanhydrideandClick"Glycosylation",Macromol.RapidCommun.31(11)(2010)991-997.
[71]F.Wan,Z.Tang,W.He,B.Chu,Achemistry/physicspathwaywithnanofibrousscaffoldsforgenedelivery,PCCP12(39)(2010)12379-12389.
[72]X.Pang,X.Zhuang,Z.Tang,X.Chen,Polylacticacid(PLA):Research,developmentandindustrialization,BiotechnologyJournal5(11)(2010)1125-1136.
[73]Z.H.Tang,C.Q.Qiu,J.R.McCutcheon,K.Yoon,H.Y.Ma,D.F.Fang,E.Lee,C.Kopp,B.S.Hsiao,B.Chu,DesignandFabricationofElectrospunPolyethersulfoneNanofibrousScaffoldforHigh-FluxNanofiltrationMembranes,JournalofPolymerSciencePartB-PolymerPhysics47(22)(2009)2288-2300.
[74]Z.Tang,J.Wei,L.Yung,B.Ji,H.Ma,C.Qiu,K.Yoon,F.Wan,D.Fang,B.S.Hsiao,B.Chu,UV-curedpoly(vinylalcohol)ultrafiltrationnanofibrousmembranebasedonelectrospunnanofiberscaffolds,J.Membr.Sci.328(1-2)(2009)1-5.
[75]Z.Tang,V.C.Gibson,rac-Lactidepolymerizationusingaluminumcomplexesbearingtetradentatephenoxy-amineligands,Eur.Polym.J.43(1)(2007)150-155.
[76]Y.K.Yang,Z.H.Tang,X.Pang,H.Z.Du,X.S.Chen,X.B.Jing,Stereoselectivepolymerizationofrac-lactideinitiatedbyachiralSchiff-baseisopropoxidealuminumcomplex,Chem.J.Chin.Univ.-Chin.27(2)(2006)352-355.
[77]Z.Tang,X.Pang,J.Sun,H.Du,X.Chen,Five-coordinatedactivespeciesinthestereoselectivepolymerizationofrac-lactideusingN,N'-(2,2-dimethyl-1,3-propylene)bis(3,5-di-tert-butyl-salicylideneimine)aluminumcomplexes,JournalofPolymerScienceParta-PolymerChemistry44(16)(2006)4932-4938.
[78]Z.H.Tang,Y.K.Yang,X.Pang,J.L.Hu,X.S.Chen,N.H.Hu,X.B.Jing,Controlledandstereospecificpolymerizationofrac-lactidewithasingle-siteethylaluminumandalcoholinitiatingsystem,J.Appl.Polym.Sci.98(1)(2005)102-108.
[79]J.L.Hu,Z.H.Tang,X.Y.Qiu,X.Pang,Y.K.Yang,X.S.Chen,X.B.Jing,Formationofflower-orcake-shapedstereocomplexparticlesfromthestereomultiblockcopoly(rac-lactide)s,Biomacromolecules6(5)(2005)2843-2850.
[80]J.Hu,Z.Tang,X.Qiu,Y.Han,Q.Du,X.Chen,X.Jing,EffectsofStereoregularityofMultiblockCopoly(rac-lactide)sonStereocomplexMicroparticlesandTheirInsulinDelivery,Macromol.Biosci.5(12)(2005)1193-1199.
[81]H.L.Guan,Z.G.Xie,Z.H.Tang,X.Y.Xu,X.S.Chen,X.B.Jing,Preparationofblockcopolymerofepsilon-caprolactoneand2-methyl-2-carboxyl-propylenecarbonate,Polymer46(8)(2005)2817-2824.
[82]C.Deng,G.Z.Rong,H.Y.Tian,Z.H.Tang,X.S.Chen,X.B.Jing,Synthesisandcharacterizationofpoly(ethyleneglycol)-b-poly(L-lactide)-b-poly(L-glutamicacid)triblockcopolymer,Polymer46(3)(2005)653-659.
[83]Z.H.Tang,X.S.Chen,Y.K.Yang,X.Pang,J.R.Sun,X.F.Zhang,X.B.Jing,Stereoselectivepolymerizationofrac-lactidewithabulkyaluminum/Schiffbasecomplex,JournalofPolymerScienceParta-PolymerChemistry42(23)(2004)5974-5982.
[84]Z.H.Tang,X.S.Chen,X.Pang,Y.K.Yang,X.F.Zhang,X.B.Jing,Stereoselectivepolymerizationofrac-lactideusingamonoethylaluminumSchiffbasecomplex,Biomacromolecules5(3)(2004)965-970.
[85]J.R.Sun,Z.K.Hong,L.X.Yang,Z.H.Tang,X.S.Chen,X.B.Jing,Studyoncrystallinemorphologyofpoly(L-lactide)-poly(ethyleneglycol)diblockcopolymer,Polymer45(17)(2004)5969-5977.
[86]Z.H.Tang,X.S.Chen,Q.Z.Hang,X.C.Bian,L.X.Yang,L.H.Piao,X.B.Jing,Strontium-basedinitiatorsystemforring-openingpolymerizationofcyclicesters,JournalofPolymerScienceParta-PolymerChemistry41(13)(2003)1934-1941.
[87]G.Z.Rong,M.X.Deng,C.Deng,Z.H.Tang,L.H.Piao,X.S.Chen,X.B.Jing,Synthesisofpoly(epsilon-caprolactone)-b-poly(gamma-benzyl-L-glutamicacid)blockcopolymerusingaminoorganiccalciumcatalyst,Biomacromolecules4(6)(2003)1800-1804.
專利目錄（部分）
1. 湯朝暉；孫環(huán)嬌；于海洋；呂世賢；張大為；陳學(xué)思一種高分子抗腫瘤前藥及其制備方法.CN201410417521.7,2014.
2. 湯朝暉;李明強(qiáng);于海洋;宋萬通;陳學(xué)思改性聚多糖及其制備方法.CN201410133893.7,2014.
3. 湯朝暉;李明強(qiáng);林堅(jiān);宋萬通;陳學(xué)思聚多巴胺納米粒子的應(yīng)用.CN201410177537.5,2014.
4. 湯朝暉;李明強(qiáng);高中輝;于海洋;陳學(xué)思一種聚苯胺納米粒子的制備方法及其應(yīng)用.CN201410177564.2,2014.
5. 湯朝暉；于海洋；宋萬通；李明強(qiáng)；陳學(xué)思阿霉素復(fù)合物及其制備方法.CN201310002466.0,2013.
6. 湯朝暉；宋萬通；于海洋；李明強(qiáng)；陳學(xué)思二氯-1,2-環(huán)己二胺合鉑配合物及其制備方法.CN201310361430.1,2013.
7. 湯朝暉；呂世賢；陳學(xué)思；李明強(qiáng)；宋萬通；于海洋氨基酸嵌段共聚物及其制備方法和復(fù)合物.CN201310009638.7,2013.
8. 湯朝暉；李明強(qiáng)；宋萬通；陳學(xué)思一種二價(jià)雙核鉑配合物及其制備方法.CN201310361461.7,2013.
9. 湯朝暉；李明強(qiáng)；陳學(xué)思；張影乙二胺四乙酸雙核鉑配合物及其制備方法.CN201310449569.1,2013.
10. 湯朝暉;李雪;于海洋;張大為;宋萬通;陳學(xué)思一種創(chuàng)傷止血敷料的制備方法.CN201310547279.0,2013.
11. 湯朝暉;李明強(qiáng);林堅(jiān);宋萬通;呂世賢;陳學(xué)思共擔(dān)載順鉑和阿霉素的復(fù)合物、膠束及膠束的制備方法.CN201310039396.6,2013.
12. 孫海;湯朝暉;許午;高戰(zhàn)團(tuán);莊秀麗;陳學(xué)思一種紫杉醇高分子鍵合藥及其制備方法.CN201310588848.6,2013.
13. 湯朝暉;于海洋;宋萬通;李明強(qiáng);莊秀麗;陳學(xué)思順鉑配合物及其制備方法.CN201210382696.X,2012.
14. 湯朝暉;宋萬通;呂世賢;于海洋;陳學(xué)思一種聚乙二醇-聚β-胺酯嵌段共聚物及其制備方法.CN201210311209.0,2012.
15. 湯朝暉;宋萬通;李明強(qiáng);丁建勛;于海洋;陳學(xué)思一種聚氨基酸接枝共聚物及其制備方法.CN201210391089.X,2012.
16. 湯朝暉;李明強(qiáng);宋萬通;呂世賢;陳學(xué)思;莊秀麗阿霉素納米粒及其制備方法.CN201210034414.7,2012.
17. 湯朝暉;李明強(qiáng);宋萬通;丁建勛;陳學(xué)思;莊秀麗阿霉素復(fù)合物、膠束及膠束的制備方法.CN201210034443.3,2012.
18. 湯朝暉;李明強(qiáng);宋萬通;陳學(xué)思;陳杰;莊秀麗順鉑配合物及其制備方法.CN201210034430.6,2012.
19. 湯朝暉;黃月;陳學(xué)思一種順鉑配合物及其制備方法.CN201210430624.8,2012.
20. 陳學(xué)思;趙麗;肖春生;丁建勛;何盼;湯朝暉聚合物、葡萄糖納米凝膠、葡萄糖納米凝膠組合物及其制備方法.CN201210512665.1,2012.
21. 莊秀麗;丁建勛;肖春生;賀超良;湯朝暉;陳學(xué)思聚氨基酸接枝共聚物及其制備方法.CN201110023705.1,2011.
22. 莊秀麗;丁建勛;栗迪;湯朝暉;陳學(xué)思聚氨基酸嵌段共聚物及其制備方法.CN201110343619.9,2011.
23. 湯朝暉;趙麗;丁建勛;肖春生;何盼;陳學(xué)思共聚物、葡萄糖敏感膠束、葡萄糖敏感載藥膠束及其制備方法.CN201110260560.7,2011.
24. 湯朝暉;趙麗;丁建勛;何盼;肖春生;莊秀麗;陳學(xué)思一種胰島素載藥微球及其制備方法.CN201110023708.5,2011.
25. 湯朝暉;栗迪;丁建勛;孫海;莊秀麗;陳學(xué)思嵌段共聚物及其制備方法.CN201110325770.X,2011.
26. 湯朝暉;栗迪;丁建勛;孫海;莊秀麗;陳學(xué)思抗腫瘤前藥及其制備方法.CN201110149748.4,2011.
27. 陳學(xué)思;何盼;湯朝暉;莊秀麗;林琳胰島素載藥微球及其制備方法.CN201110368851.8,2011.
28. 莊秀麗;高曉曄;湯朝暉;陳學(xué)思一種聚(L-谷氨酸)/聚丙烯酸水凝膠及其制備方法.CN201010130914.1,2010.
29. 莊秀麗;丁建勛;趙麗;肖春生;湯朝暉;陳學(xué)思一種聚合物微凝膠及其制備方法.CN201010130890.X,2010.
30. 莊秀麗;丁建勛;肖春生;成一龍;趙麗;湯朝暉;陳學(xué)思聚（L-谷氨酸）均聚物、無規(guī)共聚物、接枝共聚物及其制備方法.CN201010563665.5,2010.
31. 莊秀麗;丁建勛;湯朝暉;陳學(xué)思一種功能化聚酯及其制備方法.CN201010130905.2,2010.
32. 莊秀麗;丁建勛;湯朝暉;陳學(xué)思聚合物納米水凝膠及其制備方法.CN201010561226.0,2010.
33. 莊秀麗;丁建勛;高曉曄;肖春生;湯朝暉;陳學(xué)思聚合物納米水凝膠及其制備方法.CN201010563357.2,2010.
34. 莊秀麗;丁建勛;肖春生;趙長(zhǎng)穩(wěn);湯朝暉;陳學(xué)思氯乙醇功能化聚(L-谷氨酸)均聚與無規(guī)共聚物及制法和應(yīng)用.CN200910218013.5,2009.

研究方向  Researchdirection 
1、生物醫(yī)用高分子材料
2、藥物緩控釋高分子載體
3、納米藥物