王慧，女，中國藥科大學(xué)副教授，碩士生導(dǎo)師，江蘇省微生物學(xué)與免疫學(xué)會(huì)理事，江蘇省“青藍(lán)工程”優(yōu)秀骨干教師，江蘇省“六大人才高峰”第八批高層次人才。2008年畢業(yè)于南京醫(yī)科大學(xué)，獲免疫學(xué)博士學(xué)位。1999年獲中山醫(yī)科大學(xué)（中山大學(xué)中山醫(yī)學(xué)院）免疫學(xué)碩士學(xué)位，1992年獲徐州醫(yī)學(xué)院臨床醫(yī)學(xué)學(xué)士學(xué)位。研究方向?yàn)樯�物學(xué)，目前主要從事抗腫瘤藥物的研究，尤其是多糖類和多肽類抗腫瘤藥物藥效與機(jī)制的研究。近年來先后主持或參與國家科技重大專項(xiàng)、國家自然科學(xué)基金、教育部基金和江蘇省科技計(jì)劃項(xiàng)目等。目前發(fā)表學(xué)術(shù)論文40余篇，獲得市級科技進(jìn)步獎(jiǎng)2項(xiàng)。長期從事本科生的《醫(yī)學(xué)微生物學(xué)與免疫學(xué)》、《微生物學(xué)與免疫學(xué)》、《免疫學(xué)技術(shù)》等課程的教學(xué)工作，教學(xué)效果優(yōu)秀，發(fā)表教學(xué)論文4篇，獲得校級教學(xué)成果二等獎(jiǎng)3項(xiàng)。

近三年代表性論文：

1.Mengyun Ke1, Hui Wang1, Min Zhang, Yuwei Tian, Yizhou Wang, Bing Li, Jie Yu, Jie Dou, Changlin Zhou. The anti-lung cancer activity of SEP is mediated by the activation and cytotoxicity of NK cells via TLR2/4 in vivo. Biochemical Pharmacology.2014,89:119-130.

2. Yuwei Tian1, Hui Wang1, Bing Li, Mengyun Ke, Jing Wang, Jie Dou, Changlin Zhou*. The cathelicidin-BF Lys16 mutant Cbf-K16 selectively inhibits non-small cell lung cancer proliferation in vitro. Oncology reports, 2013, 30:2502-2510.

3.Hui Wang1 , Mengyun Ke1, Yuwei Tian, Jing Wang, Bing Li, Yizhou Wang, Jie Dou, Changlin Zhou*. BF-30 selectively inhibits melanoma cell proliferation via cytoplasmic membrane permeabilization and DNA-binding in vitro and in B16F10-bearing mice. European Journal of Pharmacology, 2013 (707) 1–10.

4.Qingru Hao1, Hui Wang1, Jing Wang, Jie Dou, Min Zhang, Weidong Zhou, Changlin Zhou*. Effective antimicrobial activity of Cbf-K16 and Cbf-A7A13 against NDM-1-carrying Escherichia coli by DNA binding after penetrating the cytoplasmic membrane in vitro，Journal of Peptide science，2013, 19(3):173-180.

5.Mengyu Wang 1, Hui Wang 1, Ying Tang, Di Kang, Mengyun Ke, Jie Dou, Tao Xi *, Changlin Zhou *，Effective inhibition of a Strongylocentrotus nudus eggs polysaccharide against hepatocellular carcinoma is mediated via immunoregulation in vivo. Immunology Letters, 2011; 141(1):74-82.

6.Wang H1, Wang MY1, Chen J1, Tang Y, Dou J, Yu J , Xi T *, Zhou CL *.A polysaccharide from Strongylocentrotus nudus eggs protects against myelosuppression and immunosuppression in cyclophosphamide-treated mice. Int Immunopharmacol 2011;11(11):1946-1953.）

招生方向：生物學(xué)

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