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分類:導(dǎo)師信息 來源:中國(guó)考研網(wǎng) 2016-07-11 相關(guān)院校:中國(guó)藥科大學(xué)
馮芳,藥物分析學(xué)博士,教授、博士生導(dǎo)師;教育部藥物質(zhì)量與安全預(yù)警重點(diǎn)實(shí)驗(yàn)室學(xué)術(shù)帶頭人。2000-2001年日本歧阜藥科大學(xué)藥學(xué)部高級(jí)訪問學(xué)者。
研究方向藥物質(zhì)量研究與評(píng)價(jià)
研究?jī)?nèi)容藥物質(zhì)量分析方法建立研究、藥物體內(nèi)過程分析研究、手性藥物拆分及體內(nèi)立體選擇性藥代動(dòng)力學(xué)研究、中藥(復(fù)方)藥效物質(zhì)基礎(chǔ)研究。
學(xué)術(shù)兼職國(guó)家藥典委員會(huì)委員、國(guó)家獸藥典委員會(huì)委員、國(guó)家藥監(jiān)局保健食品安全和技術(shù)規(guī)范專家委員會(huì)委員;國(guó)家科學(xué)技術(shù)獎(jiǎng)勵(lì)評(píng)審專家;國(guó)家藥監(jiān)局保健食品、化妝品、獸藥評(píng)審專家;國(guó)家科技專家?guī)煸趲鞂<遥唤逃扛咝M性u(píng)議專家;江蘇省新藥及保健食品審評(píng)專家!端幬锓治鲭s志》、《中國(guó)藥科大學(xué)學(xué)報(bào)》編委。
人才計(jì)劃及主要榮譽(yù)江蘇省“333高層次人才培養(yǎng)工程”首批中青年科學(xué)技術(shù)帶頭人;青藍(lán)工程江蘇省中青年學(xué)術(shù)帶頭人;“十五”國(guó)家級(jí)重點(diǎn)教材《藥物分析》編委、省一類精品課程主要成員;《有機(jī)光譜分析》(副主編)獲國(guó)家醫(yī)藥管理局科技進(jìn)步三等獎(jiǎng);江蘇省優(yōu)秀研究生課程《藥物光譜分析選論》負(fù)責(zé)人;2007、2009、2010年江蘇省優(yōu)秀研究生論文導(dǎo)師,2010年、2012年圣和研究生創(chuàng)新成果二等獎(jiǎng)導(dǎo)師。
近年來科研工作:
1.國(guó)家自然科學(xué)基金項(xiàng)目負(fù)責(zé)人。
2.江蘇省科技廳科技支撐計(jì)劃項(xiàng)目負(fù)責(zé)人。
3.科技部重大新藥創(chuàng)制項(xiàng)目子課題負(fù)責(zé)人。
4.企業(yè)委托新藥質(zhì)量研究、體內(nèi)過程分析研究、代謝產(chǎn)物分析研究等項(xiàng)目負(fù)責(zé)人。
近年來代表性論文、論著:
1.An untargeted metabolomics-driven approach based on LC–TOF/MS and LC–MS/MS for the screening of xenobiotics and metabolites of Zhi-Zi-Da-Huang decoction in rat plasma. Journal of Pharmaceutical and Biomedical Analysis. 2015,115: 315–322 .
2.An effective integrated method for comprehensive identification of eighty-five compounds in Zhi-Zi-Da-Huang decoction by HPLC-DAD-ESI-MS (TOF) and HPLC-DAD-ESI-MS/MS (QqQ) without the help of reference standards. Analytical method. 2014, 6:4312-4327.
3.Network Pharmacology-Based Antioxidant Effect Study of Zhi-Zi-Da-Huang Decoction for Alcoholic Liver Disease. Evidence-Based Complementary and Alternative Medicine. 2015, 1- 6.
4.Optimization of the separation and determination of nitidine and chelerythrine in zanthoxylum nitidum by high-performance liquid chromatography with fluorescence detection. J Chromatogr Sci. 2014 , 52(2):164-168.
5.Effect of aqueous extract and fractions of Zhi-Zi-Hou-Pu decoction against depression in inescapable stressed mice: restoration of monoamine neurotransmitters in discrete brain regions. Pharm Biol. 2013, 51(2):213-20.
6.A highly sensitive nonenzymatic glucose sensor based on CuO nanowires. Microchim Acta. 2012, 176:411-417.
7.Pharmacokinetics of Geniposide in Zhi-Zi-Hou-Pu Decoction and in Different Combinations of its Constituent Herbs. Phytotherapy Research. 2012, 26: 67-72
8.Pyrosequencing on nicked dsDNA generated by nicking endonucleases. Analytical Chemistry. 2010, 82(5):2074-81.
9.Determination of selected elements in aqueous extractions of a traditional Chinese medicine formula by ICP-MS and FAAS: evaluation of formula rationality. Analytical Letters, 2010, 43: 983-992.
10.Identification of components in Zhi-Zi-Da-Huang decoction by HPLC coupled with electrospray ionization tandem mass spectrometry, photodiode and fluorescence detectors. Journal of Pharmaceutical and Biomedical Analysis,.2009, 49, 1157-1165.
11.Evaluation of hepatoprotective effect of Zhi-Zi-Da-Huang decoction and its two fractions against acute alcohol-induced liver injury in rats. Journal of Ethnophamacology. 2009, 126, 273-279.
12.Influences of urinary pH on the pharmacokinetics of three amphetamine-type stimulants using a new high-performance liquid chromatographic method. Journal of Pharmaceutical Science. 2009, 98(2):728-38.
13.Development of a new pre-derivatization LC method for analysis of branched-chain and aromatic amino acids in rat plasma and to monitor their dynamic variation as a result of acute hepatic injury. Chromatographia, 2009, 70, 57-65.
14.主編《藥物分析》,東南大學(xué)出版社,2011年。
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