石磊，博士，藥學(xué)院藥物化學(xué)教研室，碩士生導(dǎo)師。

學(xué)習(xí)和工作經(jīng)歷：

2005年6月畢業(yè)于南京大學(xué)生物科學(xué)專(zhuān)業(yè)，2010年獲南京大學(xué)生物學(xué)博士學(xué)位，同年7月進(jìn)入中國(guó)藥科大學(xué)任教。2008年獲教育部自然科學(xué)獎(jiǎng)二等獎(jiǎng)（第3完成人）。

研究方向：

1.新藥分子設(shè)計(jì)與合成研究；

2.藥物合成新方法及新工藝研究。

承擔(dān)科研項(xiàng)目：

1.主持國(guó)家自然科學(xué)基金青年科學(xué)基金項(xiàng)目（21102182）；

2.主持江蘇省自然科學(xué)基金面上項(xiàng)目（BK2012760）；

3.主持教育部博士點(diǎn)新教師基金（20110096120008）；

4.參與國(guó)家自然科學(xué)基金面上項(xiàng)目（21172265）。

主要研究成果：

1.Lei Shi*, Ting-Ting Wu, Zhi Wang, Jia-Yu Xue, Yun-Gen Xu*. Discovery of N-(2-phenyl-1H-benzo[d]imidazol-5-yl)quinolin-4-amine derivatives as novel VEGFR-2 kinase inhibitors. Eur. J. Med. Chem., 2014, 84, 698-707.
2.Zhi Wang, Yi-Qiao Fan, Lei Shi* & Yun-Gen Xu*. Synthesis, crystal structure, and biological activities of a Zn(II) complex with a Se substituted Schiff base. J. Coord. Chem., 2013, 66(11), 2032-2038.
3.WANG Zhi, FAN Yi-Qiao, LUO Dan-Meng, SHI Lei*. Syntheses, Crystal Structures and Antitumor Activities of Two Nicotinamides. Chinese J. Struct. Chem., 2013,32(5), 631-636.
4.Lei Shi*, Lu Wang, Zhi Wang, Hai-Liang Zhu*, Qiao Song. Synthesis of novel cinnamanilides as potential immunosuppressive agents. Eur. J. Med. Chem., 2012, 47, 585-593.
5.Lei Shi, Zi-Lin Li, Ying Yang, Zhen-Wei Zhu, Hai-Liang Zhu. Design of novel N-phenylnicotinamides as selective cyclooxygenase-1 inhibitors. Bioorg. Med. Chem. Lett. 2011, 21, 121–124.
6.Ying Yang, Lei Shi (cofirst author), Yang Zhou, Huan-Qiu Li, Zhen-Wei Zhu, Hai-Liang Zhu. Design, synthesis and biological evaluation of quinoline amide derivatives as novel VEGFR-2 inhibitors. Bioorg. Med. Chem. Lett. 2010, 20, 6653-6656.
7.Lei Shi, Rui-Qin Fang, Zhen-Wei Zhu, Ying Yang, Kui Cheng, Wei-Qing Zhong, Hai-Liang Zhu. Design and synthesis of potent inhibitors of β-Ketoacyl-Acyl carrier protein synthase III (FabH) as potential antibacterial agents. Eur. J. Med. Chem. 2010, 45, 4358-4364.
8.Lei Shi, Ying Yang, Zi-Lin Li, Zhen-Wei Zhu, Chang-Hong Liu , Hai-Liang Zhu. Design of novel nicotinamides as potent and selective monoamine oxidase A inhibitors. Bioorg. Med. Chem. 2010, 18, 1659-1664.

聯(lián)系方式：

通信地址：南京市童家巷24號(hào)，中國(guó)藥科大學(xué)藥學(xué)院藥物化學(xué)教研室，郵編210009；

Email:shilei@cpu.edu.cn